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KMID : 0360220090500071050
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Journal of the Korean Ophthalmological Society
2009 Volume.50 No. 7 p.1050 ~ p.1059
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The Comparison of Macular Thickness Measurements and Repeatabilities Between Time Domain and Spectral Domain OCT
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Moon Sung-Woon
Kim Eung-Suk
Yu Seung-Young
Hyung Woo Kwak
Kim Young-Gyun
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Abstract
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Purpose: To compare macular thickness measurements obtained from time domain optical coherence tomography (TD-OCT) and 2 spectral domain (SD) OCTs and to evaluate their repeatability and agreement in normal subjects and diabetic macular edema patients.
Methods: Fifty-four healthy, normal subjects and 26 diabetic macular edema patients were participated in this study. In a randomly selected eye from each subject, two serial macular measurements were obtained from TD-OCT (Stratus OCT) and SD-OCTs (Cirrus HD-OCT, Spectralis HRA+OCT) by an experienced technician in random order. Nine areas of macular thickness map and repeatabilities obtained by the 3 OCTs were compared.
Results: In relative repeatability, SD-OCT showed better results overall compared to TD-OCT. Macular thickness was greatest in the Spectralis HRA+OCT in both normal subjects and diabetic macular edema patients, followed by Cirrus HD-OCT and Stratus OCT. In normal subjects, regardless of the type of comparison between the machines there was a statistically significant difference in all 9 areas.
Conclusions: While the TD-OCT and the 2 SD-OCTs are reliable for macular thickness measurement, SD-OCT has better measurement repeatability compared with TD-OCT. Because macular measurements obtained from the 3 OCT systems cannot be interchanged, an effort should be made to standardize the measurement of each system.
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KEYWORD
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Macular thickness measurement, Repeatability, Spectral-domain OCT, Time-domain OCT
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